Compounding professionals can create personalized treatments for various dermatologic issues. Compounding pharmacists enhance both the aesthetic and therapeutic qualities of customized medications, providing unique alternatives and benefits for dermatology. We can compound medications in cosmetically appealing bases, offering options that are non-comedogenic, hypoallergenic, oil-free, paraben-free, and petrolatum-free. Combining compatible drugs into a single dosage form can simplify medication administration and improve patient compliance. We often create unique formulations that physicians develop to address the specific needs of their patients, as well as “tried and true” formulas learned during professional training.